Considerations for Adding Minimally/Microinvasive Glaucoma Surgery (MIGS) to a Planned Cataract Surgery
DOI:
https://doi.org/10.58931/cect.2024.3347Abstract
Glaucoma is a progressive optic neuropathy defined by retinal ganglion cells loss and characteristic visual field loss. It is a leading cause of irreversible blindness and affects over 60 million people worldwide. Its prevalence is estimated to increase to 111.8 million by 2040. Intraocular pressure (IOP) is a major clinically modifiable risk factor for glaucoma. Thus, glaucoma therapy aims to reduce the IOP using medications, lasers (e.g., selective laser trabeculoplasty) or surgery. Historically, surgery has been reserved for advanced glaucoma and in cases with poorly controlled pressure despite medical and laser treatment. For decades, trabeculectomy and tube shunt devices have been the predominant surgical methods for lowering ocular pressure. However, these traditional surgeries are invasive requiring significant manipulation of ocular tissue and have significant post-operative complication rates. Many patients have fallen in the gap of needing more pressure lowering but not enough to justify a higher risk surgery. Fortunately, the landscape of glaucoma surgery has rapidly evolved over the past 20 years with the emergence of minimally/micro- invasive glaucoma surgery (MIGS).
MIGS is often performed as an adjunct to cataract surgery. As such, there is minimal added long-term risk if the procedure is done in the same space as the already planned cataract surgery. This represents a large group of patients, some of whom would not have been considered as glaucoma surgical candidates in the past. The clinician is now faced with the question, “Should I add MIGS to the cataract surgery?” In this paper, we suggest a series of questions to ask about each case in order to help make a patient-centred decision.
References
Tham YC, Li X, Wong TY, et al. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology. 2014;121(11):2081-90. DOI: https://doi.org/10.1016/j.ophtha.2014.05.013
Pereira ICF, van de Wijdeven R, Wyss HM, et al. Conventional glaucoma implants and the new MIGS devices: a comprehensive review of current options and future directions. Eye (Lond). 2021;35(12):3202-21. DOI: https://doi.org/10.1038/s41433-021-01595-x
Gedde SJ, Schiffman JC, Feuer WJ, , et al. Three-year follow-up of the tube versus trabeculectomy study. Am J Ophthalmol. 2009;148(5):670-84. DOI: https://doi.org/10.1016/j.ajo.2009.06.018
Saheb H, Ahmed IIK. Micro-invasive glaucoma surgery: current perspectives and future directions. Curr Opin Ophthalmol. 2012;23(2):96-104. DOI: https://doi.org/10.1097/ICU.0b013e32834ff1e7
Esfandiari H, Shah P, Torkian P, et al. Five-year clinical outcomes of combined phacoemulsification and trabectome surgery at a single glaucoma center. Graefes Arch Clin Exp Ophthalmol. 2019;257(2):357-62. DOI: https://doi.org/10.1007/s00417-018-4146-y
Wang SY, Singh K, Stein JD, et al. Ocular Antihypertensive medication use after istent implantation concurrent with cataract surgery vs. cataract surgery alone in a large US health care claims database. JAMA Ophthalmol. 2019;137(1):21-7. DOI: https://doi.org/10.1001/jamaophthalmol.2018.4461
Balas M, Mathew DJ. Minimally invasive glaucoma surgery: a review of the literature. Vision (Basel). 2023;7(3). DOI: https://doi.org/10.3390/vision7030054
Koduri VA, Reddy AK, Patnaik JL,et al. Endoscopic cyclophotocoagulation combined with phacoemulsification increases risk of persistent anterior uveitis compared to phacoemulsification surgery alone. Clin Ophthalmol. 2021;15:437-43. DOI: https://doi.org/10.2147/OPTH.S294791
Yap TE, Zollet P, Husein S, et al. Endocyclophotocoagulation combined with phacoemulsification in surgically naive primary open-angle glaucoma: three-year results. Eye (Lond). 2022;36(10):1890-5. DOI: https://doi.org/10.1038/s41433-021-01734-4
Lee GA, Porter AJ, Vincent RA, et al. Combined phacoemulsification and microinvasive glaucoma surgery in comparison to phacoemulsification alone for open angle glaucoma. Eye (Lond). 2020;34(2):312-8. DOI: https://doi.org/10.1038/s41433-019-0459-2
Richter GM, Takusagawa HL, Sit AJ, et al. Trabecular procedures combined with cataract surgery for open-angle glaucoma: a report by the American Academy of Ophthalmology. Ophthalmology. 2024;131(3):370-82. DOI: https://doi.org/10.1016/j.ophtha.2023.10.009
Samuelson TW, Katz LJ, Wells JM, et al, Group USiS. Randomized evaluation of the trabecular micro-bypass stent with phacoemulsification in patients with glaucoma and cataract. Ophthalmology. 2011;118(3):459-67. DOI: https://doi.org/10.1016/j.ophtha.2010.07.007
Ahmed IIK, De Francesco T, Rhee D, et al. Long-term outcomes from the HORIZON randomized trial for a Schlemm’s canal microstent in combination cataract and glaucoma surgery. Ophthalmology. 2022;129(7):742-51. DOI: https://doi.org/10.1016/j.ophtha.2022.02.021
Samuelson TW, Sarkisian SR, Jr., Lubeck DM, et al. Prospective, randomized, controlled pivotal trial of an Ab interno implanted trabecular micro-bypass in primary open-angle glaucoma and cataract: two-year results. Ophthalmology. 2019;126(6):811-21. DOI: https://doi.org/10.1016/j.ophtha.2019.03.006
Montesano G, Ometto G, Ahmed IIK, et al. Five-year visual field outcomes of the HORIZON trial. Am J Ophthalmol. 2023;251:143-55. DOI: https://doi.org/10.1016/j.ajo.2023.02.008
Craven ER, Katz LJ, Wells JM, et al. Cataract surgery with trabecular micro-bypass stent implantation in patients with mild-to-moderate open-angle glaucoma and cataract: two-year follow-up. J Cataract Refract Surg. 2012;38(8):1339-45. DOI: https://doi.org/10.1016/j.jcrs.2012.03.025
Hengerer FH, Auffarth GU, Conrad-Hengerer I. iStent inject trabecular micro-bypass with or without cataract surgery yields sustained 5-year glaucoma control. Adv Ther. 2022;39(3):1417-31. DOI: https://doi.org/10.1007/s12325-021-02039-4
Tojo N, Hayashi A. The outcomes of trabectome surgery in patients with low, middle, and high preoperative intraocular pressure. Clin Ophthalmol. 2020;14:4099-108. DOI: https://doi.org/10.2147/OPTH.S285883
Kuerten D, Walter P, Baumgarten S, et al. 12-month outcomes of ab interno excisional goniotomy combined with cataract surgery in primary open-angle glaucoma and normal tension glaucoma. Int Ophthalmol. 2023;43(8):2605-12. DOI: https://doi.org/10.1007/s10792-023-02659-5
Dorairaj SK, Seibold LK, Radcliffe NM, et al. 12-month outcomes of goniotomy performed using the Kahook dual blade combined with cataract surgery in eyes with medically traeted glaucoma. Adv Ther. 2018;35(9):1460-9. DOI: https://doi.org/10.1007/s12325-018-0755-4
Ventura-Abreu N, Garcia-Feijoo J, Pazos M, et al. Twelve-month results of ab interno trabeculectomy with Kahook Dual Blade: an interventional, randomized, controlled clinical study. Graefes Arch Clin Exp Ophthalmol. 2021;259(9):2771-81. DOI: https://doi.org/10.1007/s00417-021-05213-0
Devience EX, Devience SJ, Villarreal G, et al. Needle goniotomy decreases early intraocular pressure spike compared with phacoemulsification alone. AJO International. 2024;1(1):100004. DOI: https://doi.org/10.1016/j.ajoint.2024.100004
Eslami Y, Mohammadi M, Safizadeh M, et al. Six-month outcomes of combined conventional needle goniotomy and phacoemulsification in eyes with early to moderate primary open-angle and pseudoexfoliation glaucoma and ocular hypertension. Indian J Ophthalmol. 2022;70(6):2030-5. DOI: https://doi.org/10.4103/ijo.IJO_2969_21
Wan Y, Cao K, Wang J, et al. Gonioscopy-assisted transluminal trabeculotomy (GATT) combined phacoemulsification surgery: outcomes at a 2-year follow-up. Eye (Lond). 2023;37(6):1258-63. DOI: https://doi.org/10.1038/s41433-022-02087-2
Williamson BK, Vold SD, Campbell A, et al. Canaloplasty and trabeculotomy with the OMNI system in patients with open-engle glaucoma: two-year results from the ROMEO study. Clin Ophthalmol. 2023;17:1057-66. DOI: https://doi.org/10.2147/OPTH.S407918
Greenwood MD, Yadgarov A, Flowers BE, et al. 36-month outcomes from the prospective GEMINI study: canaloplasty and trabeculotomy combined with cataract surgery for patients with primary open-engle glaucoma. Clin Ophthalmol. 2023;17:3817-24. DOI: https://doi.org/10.2147/OPTH.S446486
Gallardo MJ, Supnet RA, Ahmed IIK. Viscodilation of Schlemm’s canal for the reduction of IOP via an ab-interno approach. Clin Ophthalmol. 2018;12:2149-55. DOI: https://doi.org/10.2147/OPTH.S177597
Koerber N, Ondrejka S. 6-year efficacy and safety of iTrack Ab-interno canaloplasty as a stand-alone procedure and combined with cataract surgery in primary open angle and pseudoexfoliative glaucoma. J Glaucoma. 2024;33(3):176-82. DOI: https://doi.org/10.1097/IJG.0000000000002311
Smith M, Byles D, Lim LA. Phacoemulsification and endocyclophotocoagulation in uncontrolled glaucoma: Three-year results. J Cataract Refract Surg. 2018;44(9):1097-102. DOI: https://doi.org/10.1016/j.jcrs.2018.06.025
Oku H, Mori K, Watanabe M, et al. Risk factors for intraocular pressure elevation during the early period post cataract surgery. Jpn J Ophthalmol. 2022;66(4):373-8. DOI: https://doi.org/10.1007/s10384-022-00918-z
Shingleton BJ, Pasternack JJ, Hung JW, et al. Three and five year changes in intraocular pressures after clear corneal phacoemulsification in open angle glaucoma patients, glaucoma suspects, and normal patients. J Glaucoma. 2006;15(6):494-8. DOI: https://doi.org/10.1097/01.ijg.0000212294.31411.92
Iancu R, Corbu C. Intraocular pressure after phacoemulsification in patients with uncontrolled primary open angle glaucoma. J Med Life. 2014;7(1):11-6.
Moore SG, Richter G, Modjtahedi BS. Factors affecting glaucoma medication adherence and interventions to improve adherence: a narrative review. Ophthalmol Ther. 2023;12(6):2863-80. DOI: https://doi.org/10.1007/s40123-023-00797-8
Samuelson TW, Singh IP, Williamson BK, et al. Quality of life in primary open-angle glaucoma and cataract: an analysis of VFQ-25 and OSDI from the iStent inject(R) Pivotal trial. Am J Ophthalmol. 2021;229:220-9. DOI: https://doi.org/10.1016/j.ajo.2021.03.007
Asrani S, Zeimer R, Wilensky J, et al. Large diurnal fluctuations in intraocular pressure are an independent risk factor in patients with glaucoma. J Glaucoma. 2000;9(2):134-42. DOI: https://doi.org/10.1097/00061198-200004000-00002
Pyfer MF, Gallardo M, Campbell A, et al. Suppression of diurnal (9am-4pm) IOP fluctuations with minimally invasive glaucoma surgery: an analysis of data from the prospective, multicenter, single-arm GEMINI study. Clin Ophthalmol. 2021;15:3931-8. DOI: https://doi.org/10.2147/OPTH.S335486
Sahlu M, Giorgis AT. Dry eye disease among Glaucoma patients on topical hypotensive medications, in a tertiary hospital, Ethiopia. BMC Ophthalmol. 2021;21(1):155. DOI: https://doi.org/10.1186/s12886-021-01917-3
Wong JKW, Leung TK, Lai JS, et al. Evaluation of adverse effects of topical glaucoma medications on trabeculectomy outcomes using the glaucoma medications intensity index. Ophthalmol Ther. 2022;11(1):387-401. DOI: https://doi.org/10.1007/s40123-021-00447-x
Yeh PH, Cheng YC, Shie SS, et al. Brimonidine related acute follicular conjunctivitis: Onset time and clinical presentations, a long-term follow-up. Medicine (Baltimore). 2021;100(29):e26724. DOI: https://doi.org/10.1097/MD.0000000000026724
Sood S, Heilenbach N, Sanchez V, et al. Cost-effectiveness analysis of minimally invasive trabecular meshwork stents with phacoemulsification. Ophthalmol Glaucoma. 2022;5(3):284-96. DOI: https://doi.org/10.1016/j.ogla.2021.09.006
Su WW, Hsieh SS, Sun MH, et al. Comparison of visual field progression rate before and after cataract surgery in patients with open-angle and angle-closure glaucoma. J Ophthalmol. 2021;2021:7655747. DOI: https://doi.org/10.1155/2021/7655747
Hirasawa K, Nakakura S, Nakao Y, et al. Changes in corneal biomechanics and intraocular pressure following cataract surgery. Am J Ophthalmol. 2018;195:26-35. DOI: https://doi.org/10.1016/j.ajo.2018.07.025
Rodrigues IA, Alaghband P, Beltran Agullo L, et al. Aqueous outflow facility after phacoemulsification with or without goniosynechialysis in primary angle closure: a randomised controlled study. Br J Ophthalmol. 2017;101(7):879-85. DOI: https://doi.org/10.1136/bjophthalmol-2016-309556
Tian T, Li M, Pan Y, et al. The effect of phacoemulsification plus goniosynechialysis in acute and chronic angle closure patients with extensive goniosynechiae. BMC Ophthalmol. 2019;19(1):65. DOI: https://doi.org/10.1186/s12886-019-1070-9
Chansangpetch S, Lau K, Perez CI, et al. Efficacy of cataract surgery with trabecular microbypass stent implantation in combined-mechanism angle closure glaucoma patients. Am J Ophthalmol. 2018;195:191-8. DOI: https://doi.org/10.1016/j.ajo.2018.08.003
Hernstadt DJ, Cheng J, Htoon HM, et al. Case series of combined iStent implantation and phacoemulsification in eyes with primary angle closure disease: one-year outcomes. Adv Ther. 2019;36(4):976-86. DOI: https://doi.org/10.1007/s12325-019-00899-5
El Sayed YM, Mettias NM, Elghonemy HME, et al. Phacoemulsification with gonioscopy-assisted transluminal trabeculotomy versus phacoemulsification alone in primary angle closure glaucoma: A randomized controlled study. Acta Ophthalmol. 2024;102(2):e195-e203. DOI: https://doi.org/10.1111/aos.15733
Xu BY, Burkemper B, Lewinger JP, et al. Correlation between intraocular pressure and angle configuration measured by OCT: the Chinese American Eye Study. Ophthalmol Glaucoma. 2018;1(3):158-66. DOI: https://doi.org/10.1016/j.ogla.2018.09.001
Porporato N, Chong R, Xu BY, et al. Angle closure extent, anterior segment dimensions and intraocular pressure. Br J Ophthalmol. 2023;107(7):927-34. DOI: https://doi.org/10.1136/bjophthalmol-2021-320453
Tran HV, Liebmann JM, Ritch R. Iridociliary apposition in plateau iris syndrome persists after cataract extraction. Am J Ophthalmol. 2003;135(1):40-3. DOI: https://doi.org/10.1016/S0002-9394(02)01842-1
Francis BA, Pouw A, Jenkins D, et al. Endoscopic cycloplasty (ECPL) and lens extraction in the treatment of severe plateau iris syndrome. J Glaucoma. 2016;25(3):e128-33. DOI: https://doi.org/10.1097/IJG.0000000000000156
Paletta Guedes RA, Gravina DM, Paletta Guedes VM, et al. Standalone implantation of 2-3 trabecular micro-bypass stents (iStent inject +/- iStent) as an alternative to trabeculectomy for moderate-to-severe glaucoma. Ophthalmol Ther. 2022;11(1):271-92. DOI: https://doi.org/10.1007/s40123-021-00424-4
Dar N, Naftali Ben Haim L, Yehezkeli V, et al. Gonioscopy-assisted transluminal trabeculotomy in patients with advanced glaucoma. Indian J Ophthalmol. 2023;71(8):3024-30. DOI: https://doi.org/10.4103/IJO.IJO_2769_22
Laroche D, Nkrumah G, Ng C. Real-world efficacy of the Hydrus microstent in Black and Afro-Latinx patients with glaucoma: a retrospective study. Ther Adv Ophthalmol. 2020;12:2515841420964311. DOI: https://doi.org/10.1177/2515841420964311
Tekcan H, Mangan MS, Imamoglu S, et al. Refractive outcomes of uneventful cataract surgery in pseudoexfoliation syndrome and pseudoexfoliation glaucoma. Korean J Ophthalmol. 2022;36(3):226-35. DOI: https://doi.org/10.3341/kjo.2021.0183
Sarkisian SR, Jr., Radcliffe N, Harasymowycz P, et al. Visual outcomes of combined cataract surgery and minimally invasive glaucoma surgery. J Cataract Refract Surg. 2020;46(10):1422-32. DOI: https://doi.org/10.1097/j.jcrs.0000000000000317
Ioannidis AS, Toteberg-Harms M, Hamann T, et al Outcomes after trabecular micro-bypass stents (iStent Inject) with cataract extraction in open-angle glaucoma. Clin Ophthalmol. 2020;14:517-24. DOI: https://doi.org/10.2147/OPTH.S239103
Chang EL, Apostolopoulos N, Mir TA, et al. Large hyphema following femtosecond laser-assisted cataract surgery (FLACS) and trabectome resulting in endocapsular hematoma. J Curr Glaucoma Pract. 2022;16(3):195-8. DOI: https://doi.org/10.5005/jp-journals-10078-1372
Manning DK, Haider A, Clement C, et al. Efficacy and safety of iStent inject implantation in manual and femtosecond laser-assisted cataract surgery before lens extraction. J Curr Glaucoma Pract. 2022;16(2):105-10. DOI: https://doi.org/10.5005/jp-journals-10078-1374
Wang JC, Campos-Moller X, Shah M, et al. Effect of endocyclophotocoagulation on refractive outcomes in angle-closure eyes after phacoemulsification and posterior chamber intraocular lens implantation. J Cataract Refract Surg. 2016;42(1):132-7. DOI: https://doi.org/10.1016/j.jcrs.2015.07.046
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