An Approach to Optic Neuropathies

Authors

  • Vivek R. Patel, MD University of California, Irvine; Gavin Herbert Eye Institute

DOI:

https://doi.org/10.58931/cect.2023.2120

Abstract

Optic neuropathies are varied in their clinical presentations, etiologies, recommended diagnostic investigations, and treatments. This article aims to provide a practical framework to guide the evaluation of a patient suspected of an optic neuropathy.

Author Biography

Vivek R. Patel, MD, University of California, Irvine; Gavin Herbert Eye Institute

Dr. Vivek Patel is Professor of Clinical Ophthalmology and Chief of Neuro-ophthalmology & Adult Strabismus at the University of California, Irvine, Gavin Herbert Eye Institute. He currently directs the Neuro-ophthalmology & Adult Strabismus fellowship at UCI and is co-director of their Neuro-ophthalmology & Orbital Surgery international fellowship. He completed medical school at the University of Saskatchewan, Ophthalmology residency at McGill University, and Neuro-Ophthalmology at the University of Southern California/Doheny Eye Institute.

References

Prasad S, Volpe NJ, Balcer LJ. Approach to optic neuropathies: clinical update. Neurologist. 2010 Jan;16(1):23-34. DOI: https://doi.org/10.1097/NRL.0b013e3181be6fad

Sadun AA, Patel VR. Differentiating Optic Nerve from Macular disease. Yanoff and Duker: Ophthalmology 3rd Edition. 2008 Mosby Inc. DOI: https://doi.org/10.1016/B978-0-323-04332-8.00158-X

Wall M. Update on Idiopathic Intracranial Hypertension. Neurol Clin. 2017 Feb;35(1):45-57. DOI: https://doi.org/10.1016/j.ncl.2016.08.004

Murphy LS, Lacy AJ, Smith AT, Shah KS. Cryptococcal meningitis in an immunocompetent patient. Am J Emerg Med. 2020 Nov;38(11):2492.e1-2492.e3. DOI: https://doi.org/10.1016/j.ajem.2020.05.115

Hickman SJ. Optic Perineuritis. Curr Neurol Neurosci Rep. 2016 Feb;16(2):16. doi:10.1007/s11910-015-0617-2. DOI: https://doi.org/10.1007/s11910-015-0617-2

Hayreh SS. Diabetic papillopathy and nonarteritic anterior ischemic optic neuropathy. Surv Ophthalmol. 2002 Nov-Dec;47(6):600-2; author reply 602. DOI: https://doi.org/10.1016/S0039-6257(02)00358-2

Teja S, Patel VR. Ischemic Optic Neuropathies: Diagnosis and Management. Int. Ophthalmol Clin. 2019 Summer; 59(3):39-57. DOI: https://doi.org/10.1097/IIO.0000000000000282

Abel A, McClelland C, Lee MS. Critical review: Typical and atypical optic neuritis. Surv Ophthalmol. 2019 Nov-Dec;64(6):770-779. DOI: https://doi.org/10.1016/j.survophthal.2019.06.001

Newman NJ, Scherer R, Langenberg P, Kelman S, Feldon S, Kaufman D, Dickersin K; Ischemic Optic Neuropathy Decompression Trial Research Group. The fellow eye in NAION: report from the ischemic optic neuropathy decompression trial follow-up study. Am J Ophthalmol. 2002 Sep;134(3):317-28. DOI: https://doi.org/10.1016/S0002-9394(02)01639-2

Passman RS, Bennett CL, Purpura JM, Kapur R, Johnson LN, Raisch DW, West DP, Edwards BJ, Belknap SM, Liebling DB, Fisher MJ, Samaras AT, Jones LG, Tulas KM, McKoy JM. Amiodarone-associated optic neuropathy: a critical review. Am J Med. 2012 May;125(5):447-53. DOI: https://doi.org/10.1016/j.amjmed.2011.09.020

Chen JJ, Bhatti MT. Clinical phenotype, radiological features, and treatment of myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG) optic neuritis. Curr Opin Neurol. 2020 Feb;33(1):47-54. DOI: https://doi.org/10.1097/WCO.0000000000000766

Optic Neuritis Study Group. The clinical profile of optic neuritis. Experience of the optic neuritis treatment trial. Arch Ophthalmol. 1991;109:1673–8. DOI: https://doi.org/10.1001/archopht.1991.01080120057025

Sadda SR, Nee M, Miller NR, Biousse V, Newman NJ, Kouzis A. Clinical spectrum of posterior ischemic optic neuropathy. Am J Ophthalmol. 2001 Nov;132(5):743-50. DOI: https://doi.org/10.1016/S0002-9394(01)01199-0

Grzybowski A, Zülsdorff M, Wilhelm H, Tonagel F. Toxic optic neuropathies: an updated review. Acta Ophthalmol. 2015 Aug;93(5):402-10. DOI: https://doi.org/10.1111/aos.12515

Marignier R, Hacohen Y, Cobo-Calvo A, Pröbstel AK, Aktas O, Alexopoulos H, Amato MP, Asgari N, Banwell B, Bennett J, Brilot F, Capobianco M, Chitnis T, Ciccarelli O, Deiva K, De Sèze J, Fujihara K, Jacob A, Kim HJ, Kleiter I, Lassmann H, Leite MI, Linington C, Meinl E, Palace J, Paul F, Petzold A, Pittock S, Reindl M, Sato DK, Selmaj K, Siva A, Stankoff B, Tintore M, Traboulsee A, Waters P, Waubant E, Weinshenker B, Derfuss T, Vukusic S, Hemmer B. Myelin-oligodendrocyte glycoprotein antibody-associated disease. Lancet Neurol. 2021 Sep;20(9):762-772. DOI: https://doi.org/10.1016/S1474-4422(21)00218-0

Weinshenker BG, Wingerchuk DM. Neuromyelitis Spectrum Disorders. Mayo Clin Proc. 2017 Apr;92(4):663-679. DOI: https://doi.org/10.1016/j.mayocp.2016.12.014

Published

2023-02-01

How to Cite

1.
Patel VR. An Approach to Optic Neuropathies. Can Eye Care Today [Internet]. 2023 Feb. 1 [cited 2024 Nov. 21];2(1):4–8. Available from: https://canadianeyecaretoday.com/article/view/2-1-1

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Section

Articles